Zhuge Liang's Southern Campaign, also known as the War of Pacification in Nanzhong, is a military campaign led by Shu Han chancellor Zhuge Liang to suppress opposing forces in the south in 225 during the Three Kingdoms period of Chinese history.

The campaign is a response to rebellions started by local governors in the southern region of Nanzhong and intrusions by the Nanman (literally: "southern barbarians").