The Battle of Naissus (268 or 269) is the defeat of a Gothic coalition by the Roman Empire under Emperor Gallienus (or Claudius II) near Naissus (Niš in present-day Serbia).

The events around the invasion and the battle are an important part of the history of the Crisis of the Third Century.The result is a great Roman victory that, combined with the effective pursuit of the invaders in the aftermath of the battle and the energetic efforts of the Emperor Aurelian, largely removes the threat from Germanic tribes in the Balkan frontier for the following decades.