The Second Macedonian War (200–197 BCE) is fought between Macedon, led by Philip V of Macedon, and Rome, allied with Pergamon and Rhodes.

The result is the defeat of Philip who is forced to abandon all his possessions in Greece.

Although the Romans declare the "freedom of the Greeks", the war marks a significant stage in increasing Roman intervention in the affairs of the eastern Mediterranean which will eventually lead to their conquest of the entire region.