Indian Wars in Upper North America describes a series of conflicts between American settlers or the federal government and the native peoples of North America before and after the American Revolutionary War.

The wars result from the arrival of European colonizers who continuously seek to expand their territory, pushing the indigenous populations westwards.

The wars are spurred by ideologies such as Manifest Destiny, which holds that the United States is destined to expand from coast to coast on the American continent, and which results in the policy of Indian removal, by which indigenous peoples are removed from the areas where Europeans are settling, either forcefully or by means of voluntary exchange of territory through treaties.