The Gulf Coast campaign or the Spanish conquest of West Florida in the Anglo-Spanish War of 1779–1783, is a series of military operations primarily directed by the governor of Spanish Louisiana, Bernardo de Gálvez against the British province of West Florida.

Begun with operations against British positions on the Mississippi River shortly after Britain and Spain went to war in 1779, Gálvez completes the conquest of West Florida in 1781 with the successful siege of Pensacola.