The Conspiracy of the Slaves (Maltese: Konfoffa tal-ilsiera), also known as the Revolt of the Slaves, is a failed plot by Muslim slaves in Hospitaller-ruled Malta to rebel, assassinate Grand Master Manuel Pinto da Fonseca and take over the island.

The revolt is to  place on 29 June 1749, but plans are leaked to the Order before it begins, and the plotters are arrested and most are later executed.