Tigranes the Great (140–55 BCE; also called Tigranes II and sometimes Tigranes I) is emperor of Armenia under whom the country becomes, for a short time, the strongest state east of the Roman Republic.

He is a member of the Artaxiad Royal House.

Under his reign, the Armenian kingdom expands beyond its traditional boundaries, allowing Tigranes to claim the title Great King, and involving Armenia in many battles against opponents such as the Parthian and Seleucid empires, and the Roman Republic.