Thomas Jamison (1752/1753 – January 27, 1811) is a prominent surgeon, government official, mercantile trader and land owner of Sydney, Australia.

Jamison is also a member of the First Fleet expedition of 11 ships that founds the Australian colony of New South Wales in 1788.

Twenty years later, he participates in the Rum Rebellion, which deposes the colony's governor, William Bligh.