John Nixon, the son of a Philadelphia shipping merchant, had signed the non-importation agreement against the Stamp Act, became active in opposing the encroachments of the English government upon American liberties, and was a member of the first committee of correspondence in Pennsylvania.
Becoming lieutenant-colonel of the third battalion of the Philadelphia Associators, a militia unit, in April 1775, he was also a member of the Committee of Safety.
From May to July 1776, he was in command of the defenses of the Delaware River at Fort Island, after which he was put in charge of the defenses of Philadelphia.
On July 8, 1776, Nixon had delivered the first public proclamation of the Declaration of Independence from the steps of the Pennsylvania State House.
Promoted colonel the same year, Nixon later served under George Washington at the Battle of Princeton, became a member of the Navy Board, and two years later was with Washington again at Valley Forge.
Robert Morris and his allies, including Fitzsimons and Nixon, supply the majority of war materials to the troops when the state fails to act.