Seleucus II Callinicus or Pogon (Greek: the epithets meaning "beautiful victor" and "bearded", respectively), was a ruler of the Hellenistic Seleucid Empire, who reigned from 246 to 225 BCE.

After the death of this father, Antiochus, he was proclaimed king by his mother, Laodice in Ephesos, while her partisans at Antioch murdered Berenice and her son, another Antiochus.