Raymond IV of Toulouse (c. 1041 or 1042 – 1105), sometimes called Raymond of St Gilles, is Count of Toulouse, Duke of Narbonne, and Margrave of Provence and one of the leaders of the First Crusade.

He is a son of Pons of Toulouse and Almodis de La Marche.

He receives Saint-Gilles with the title of "count" from his father and displaces his niece Philippa, Duchess of Aquitaine, his brother William IV's daughter, in 1094 from inheriting Toulouse.

According to an Armenian source, he had lost an eye on a pilgrimage to Jerusalem before the First Crusade, but this statement probably refers to the fact that he was one-eyed (monoculus).

He also fights against the Moors in Spain before 1096, and he is the first to join the crusade after Pope Urban II's sermon at the Council of Clermont.