Ottaviano Petrucci (born in Fossombrone on June 18, 1466 – died on May 7, 1539 in Venice), is an Italian printer.

His Harmonice Musices Odhecaton, a collection of chansons printed in 1501, is commonly misidentified as the first book of sheet music printed from movable type.

Actually that distinction belongs to the Roman printer Ulrich Han's Missale Romanum of 1476.

Nevertheless, Petrucci's later work is extraordinary for the complexity of his white mensural notation and the smallness of his font, and he does in fact print the first book of polyphony using movable type.

He also publishes numerous works by the most highly regarded composers of the Renaissance, including Josquin des Prez and Antoine Brumel.