Nyuserre Ini (also spelt as Neuserre Izi or Niuserre Isi, and sometimes Nyuserra; in Greek known as Rathoris), is a Pharaoh of Egypt during the Fifth dynasty.

He is frequently given a reign of 24 or 25 years and is dated from ca.

2445 BCE to 2421 BCE.

His prenomen, Nyuserre, means "Possessed of Re's Power".

Nyuserre was the younger son of pharaoh Neferirkare Kakai by Queen Khentkaus II, and the brother of the short-lived king Neferefre.

He is often thought to have succeeded his brother directly, but there is some evidence to suggest that Shepseskare reigned between the two, albeit only for a few weeks.

Possibly, the latter had attempted to restore the lineage of Sahure who might have been his father, deposing the lineage of Neferirkare Kakai in the process, but was unsuccessful.