Fray Nicolás de Ovando y Cáceres (Brozas, Extremadura, 1460 – Madrid, May 29, 1511) was a Spanish soldier from a noble family and a Knight of the Order of Alcántara.

He is Governor of the Indies (Hispaniola) from 1502 until 1509.

His administration is perhaps best known for its brutal treatment of the native Taíno population of Hispaniola.