Minkhaung II of Toungoo (1520s–1584) is viceroy of Toungoo (Taungoo) from 1549 to 1551 and from 1552 to 1584 during the reigns of kings Tabinshwehti, Bayinnaung and Nanda of the Toungoo Dynasty of Burma (Myanmar).

He briefly revolts against his eldest half-brother Bayinnaung from 1550 to 1551 but is pardoned by Bayinnaung.

Alongside his brothers Bayinnaung, Minye Sithu, Thado Dhamma Yaza II, Thado Minsaw and his nephew Nanda, he fights in nearly every campaign between 1552 and 1584, which serves to rebuild, expand, and defend the Toungoo Empire.

Minkhaung II is sometimes referred to as the basis for Taungoo Mingaung, one of the Thirty Seven Nats (spirits) in the official pantheon of Burmese spirits although the actual basis may have been Minkhaung I of Toungoo.