Manuel Boutoumites or Butumites (, fl.

1086–1112) is a leading Byzantine general and diplomat during the reign of Emperor Alexios I Komnenos (r. 1081–1118), and one of the emperor's most trusted aides.

He is instrumental in the Byzantine recovery of Nicaea from the Seljuk Turks, in the reconquest of Cilicia, and acts as the emperor's envoy in several missions to Crusader princes.