Lloyd Tilghman (January 26, 1816 – May 16, 1863) is a Confederate general in the American Civil War.

A railroad construction engineer by background, he is selected by the Confederate government to build two forts to defend the Tennessee and Cumberland rivers.

The location of Fort Henry on the Tennessee is vulnerable to flooding, but Tilghman had been slow to spot this, and his surrender of the fort to U.S. Grant in February 1862 is regarded as a disgrace.

Taken prisoner and exchanged, he commands a brigade in the Vicksburg campaign, and is killed by a shell at the Battle of Champion Hill, where he is widely praised for gallantry.