John R. Coffee (June 2, 1772 – July 7, 1833) was an American planter and state militia general in Tennessee.

He commands troops under General Andrew Jackson during the Creek Wars (1813–14) and during the Battle of New Orleans in the War of 1812.

During his presidency, Jackson appoints Coffee as his representative, along with Secretary of War John Eaton, to negotiate treaties with Southeast American Indian tribes to accomplish removal, a policy authorized by Congressional passage of the Indian Removal Act of 1830.

Coffee negotiates the Treaty of Dancing Rabbit Creek of 1830 with the Choctaw by which they cede their lands, and starts negotiations with the Chickasaw, but they do not conclude a treaty until after his death.