Hernando de Luque (Unknown – 1532) is a Spanish priest who travels o the New World in the sixteenth century.

Luque was born in Olvera, Andalusia, but grew up in Luque, Spain.

His last name comes from his home town.

His English name is Hernando of Luque.

Luque leaves for the Americas in 1514, arriving with the expedition of Pedrarias Dávila to Panama, where he meets Francisco Pizarro.