Francisco de las Casas y Saavedra (1461–1536) is a Spanish Conquistador in Mexico and Honduras.

Francisco de las Casas was born in Trujillo, Spain.

By 1513 las Casas is already married to Maria de Aguilar, daughter of Geronimo de Aguilar, and they maintain a house in Trujillo, where she sells a block of land in Trujillo that she owns.

They have a son, Gonzalo.

Cortés refers to Francisco de las Casas as "mi primo" in his fifth letter to the Spanish Crown.

Maria is also Cortés' cousin.