Fernando Francesco d'Ávalos, V marquis of Pescara (or Ferrante Francesco d'Ávalos; Spanish: Francisco Fernando d'Ávalos, 1489 – December 3, 1525), is an Italian condottiero of Spanish extraction.

As a general of the Spanish army, he participates in the Italian Wars.

At the Battle of Ravenna in 1512 he is taken prisoner by the French, but is released at the conclusion of the War of the League of Cambrai.

He is the chief commander of the Habsburg armies in Italy during the Habsburg-Valois Wars and defeats the French at Bicocca and Pavia.