Cuthwine, born c. 565, is a member of the House of Wessex, son of Ceawlin of Wessex.

After the deposition of his father Ceawlin from the throne of Wessex in 592 he does not inherit the throne which passes to his cousin, Ceol.

Instead he goes into exile for many decades, remaining a strong leader of the Saxons and passing on the royal line through his three sons.