Cristóvão da Gama (c. 1516 – 29 August 1542) is a Portuguese soldier, who leads a Portuguese army on a crusade in Ethiopia (1541–1543) against the Muslim army of Imam Ahmad ibn Ibrihim al-Ghazi (also known as Ahmad Gragn).

He is victorious against larger forces in four battles, but is defeated in his last battle, after which he is captured and killed.

Sir Richard Burton, in his First Footsteps in East Africa, refers to him as "the most chivalrous soldier of a chivalrous age."