Christina of Denmark (November 1521 – December 10, 1590) is a Danish princess who becomes Duchess-consort of Milan, then Duchess-consort of Lorraine.

She serves as Regent of Lorraine in the years 1545–1552 during the minority of her son.

She is also a claimant to the thrones of Denmark, Norway and Sweden in 1561-1590.

Finally, she is sovereign Lady of Tortona in 1578-1584.