Cesare Borgia (13 September 1475 or April 1476 – 12 March 1507), Duke of Valentinois, is a Spanish-Italian condottiero, nobleman, politician, and cardinal.

He is the son of Pope Alexander VI and his long-term mistress Vannozza dei Cattanei.

He is brother to Lucrezia Borgia, (Juan) Giovanni Borgia, Duke of Gandia, and Gioffre Borgia (Jofré in Valencian), Prince of Squillace.

He is half-brother to Don Pedro Luis de Borja (1460–1481) and Girolama de Borja, children of unknown mothers.