Barbatio (died 359) is a Roman general of the infantry under the command of Constantius II.

Previously he was a commander of the household troops under Gallus Caesar, but he arrestsGallus under the instruction of Constantius, thereby ensuring his promotion on the death of Claudius Silvanus.

In 359, both he and his wife Assyria are arrested and beheaded for treason against Constantius, possibly as part of a plot by Arbitio, a senior cavalry commander, and another exponent of the forms of scheming and political intrigue that become such a part of the later Roman Empire.