Artaxias II (also called Artaxes or Artashes) (reigns 34 BCE – 20 BCE) is a king of Armenia, the eldest son of Artavasdes II.

He ascends the throne when his father is taken prisoner and executed by Triumvir Mark Antony, and after his own skirmish with the Romans is forced to flee to Parthia.

With the support of the Parthians, however, he returs to Armenia and successfully makes war on Artavasdes I of Media Atropatene, an enemy of his father.

He also executes all the Romans who can be found within his borders.

Possibly as a consequence of this action, when Artaxias sends emissaries to Rome to try to secure the release of his relatives then in Roman captivity, Roman Emperor Augustus refuses him.