Padeshah Ali Mirza Safavi succeeds his father Haydar Safavi as leader of the Safaviyya, a Twelver Shi'i militant religious order, in 1488.

He is killed in 1494 by order of the Ak Koyunlu leader, Roustam, who views his former ally as a growing threat.

Ali Mirza's father and grandfather had married into the Ak Koyunlu dynasty: his mother is Alam-Shah Begum, daughter of the Ak Koyunlu leader Uzun Hasan.