Vespasian had slaughtered or enslaved the inhabitants of Betaris in the Jewish War in 68.

According to Josephus: "When he had seized upon two villages, which were in the very midst of Idumea, Betaris, and Caphartobas, he slew above ten thousand of the people, and carried into captivity above a thousand, and drove away the rest of the multitude, and placed no small part of his own forces in them, who overran and laid waste the whole mountainous country." (Josephus, The Jewish Wars, IV.viii.1)

The settlement had been demolished once again in 132–135 during the Bar Kokhba revolt.

The Romans have reestablished the city and given it a Greek name, Eleutheropolis, meaning “City of the Free."

Coins minted by Septimius Severus bear the date January 1, 200, commemorating its founding.

Eleutherpolis, where seven routes meet, has become one of the most important cities in Roman Palestine.

Eusebius in his Onomasticon will use the Roman milestones indicating the city as a central point from which the distances of other towns are measured.

Khalid bin Walid writes to Caliph Abu Bakr, informing him of the progress of his operations since his entry into Syria, and sends one-fifth of the spoils which had been won during the past few weeks.

Hardly had Bosra surrendered when an agent sent by Shurahbil to the region of Ajnadayn returns to inform the Muslims that the concentration of Roman legions is proceeding apace.

Soon they will have a vast army of ninety thousand imperial soldiers at Ajnadayn.

Khalid ibn Walid orders all the Muslim corps in Syria to concentrate at Ajnadayn and on July 30, 634, defeats the imperial army in the Battle of Ajnadayn.