After the Fall of the Western Roman Empire, Tuscia from 568 is part of the Italian Kingdom of the Lombards (Langobardia Major) until in 754 the Frankish kings intervene in the conflict with Pope Stephen II.

By the Donation of Pepin, the southern part of Tuscia around Viterbo becomes part of the newly established Papal States, while the northern part develops to the Imperial March of Tuscany after Charlemagne has finally conquered the Lombard kingdom in 773/74.

Lombardy proper becomes the nucleus of the Imperial kingdom of Italy, together with the marches of Tuscany and Verona.