The Nisqually is a Lushootseed-speaking Native American tribe in western Washington state in the United States.

They are a Southern Coast Salish people.

They are federally recognized as the Nisqually Indian Tribe, formerly known as the Nisqually Indian Tribe of the Nisqually Reservation and the Confederated Tribes of the Chehalis Reservation.

The tribe lives on a reservation in the Nisqually River valley near the river delta.

The Nisqually Indian Reservation, at 47°01′12″N 122°39′27″W, comprises 20.602 km² (7.955 sq mi) of land area on both sides of the river, in western Pierce County and eastern Thurston County.

In the 2000 census, it has a resident population of 588 persons, all in the Thurston County portion, on the southwest side of the Nisqually River.

The tribe moves onto their reservation east of Olympia, Washington, in late 1854 with the signing of the Medicine Creek Treaty.

As reaction to the unfairness of the treaty, many members of the tribe led by Chief Leschi engage and are eventually defeated by the US Army in the conflict known as the Puget Sound War in 1855-56.