Isauria, in ancient geography, is a rugged isolated district in the interior of South Asia Minor, of very different extent at different periods, but generally covering what is now the district of Bozkır and its surroundings in the Konya Province of Turkey, or the core of the Taurus Mountains.

In its coastal extension it bordered on Cilicia.

It derives its name from the contentious Isaurian tribe (which is probably Luwian) and twin settlements Isaura Palaea (Latin: Isaura Vetus, "Old Isaura") and Isaura Nea (Latin: Isaura Nova, "New Isaura").

Isaurian marauders are fiercely independent mountain people who create havoc in neighboring districts under Macedonian and Roman occupations.The permanent nucleus of Isauria is north of the Taurus range, which lies directly to south of Iconium and Lystra.

Lycaonia has all the Iconian plain; but Isauria begins as soon as the foothills are reached.

Its two original towns, Isaura Nea and Isaura Palaea, lie, one among these foothills (Doria) and the other on the watershed (Zengibar Kalesi).