Hadhramaut, Hadhramout, Hadramawt or Ḥaḍramūt is the formerly independent Qu'aiti state and sultanate encompassing a historical region of the south Arabian Peninsula along the Gulf of Aden in the Arabian Sea, extending eastwards from Yemen to the borders of the Dhofar region of Oman.

The name of the region is currently retained in the smaller Hadhramaut Governorate of the Republic of Yemen.

The people of Hadhramaut are called Hadhramis and speak Hadhrami Arabic.