Berbice is a region along the Berbice River in Guyana, which is between 1627 and 1815 a colony of the Netherlands.

After having been ceded to the United Kingdom in the latter year, it i merged with Essequibo and Demerara to form the colony of British Guiana in 1831.

In 1966, British Guiana gains independence as Guyana.After being a hereditary fief in the possession of the Van Peere family, the colony is governed by the Society of Berbice in the second half of the colonial period, akin to the neighboring colony of Suriname, which is governed by the Society of Suriname.

The capital of Berbice is at Fort Nassau until 1790.

In this year, the town of New Amsterdam, which grows around Fort Sint Andries, was made the new capital of the colony.