Anhalt-Zerbst is a principality located in Germany.

It is established for the first time in 1252 following the partition of the principality of Anhalt.

The capital of the state is located at Zerbst.

Anhalt-Zerbst ceases to exist in 1396 when it is partitioned between Anhalt-Dessau and Anhalt-Köthen.It is recreated in 1544 when Anhalt-Dessau is partitioned.

The second incarnation loses a lot of territory in 1603 when it is partitioned for a second time with some of its territory being given to Anhalt-Dessau, Anhalt-Bernburg, Anhalt-Plötzkau and Anhalt-Köthen.

Anhalt-Zerbst loses more of its territory in 1667 with Anhalt-Mühlingen and Anhalt-Dornburg being created.

In 1796, the Principality of Anhalt-Zerbst comes to an end with its territory being annexed by Anhalt-Dessau.