Agathocles, another member of the court clique in Alexandria, becomes the guardian of Ptolemy V when Sosibius retires in about 202.

Agathocles soon provokes Tlepolemus, the governor of Pelusium (Egypt's eastern frontier city), who marches on Alexandria, where his supporters rouse a mob, compelling Agathocles to resign in favor of another courtier.

The boy king, enthroned in the stadium while the mob clamors for the murderers of his parents, nods in confusion at the prompting of a courtier, and the mob searches out and butchers Agathocles and his family.

Tlepolemus, however, soon proves incompetent and is removed.

Antiochus now marches against Egypt.

The Roman Republic being embroiled in the Second Punic War with Carthage, ...