The Sassanid occupation of Iraq, about which little information exists, lasts until 636.

The north is devastated by battles fought between Romans and Sassanids.

For the most part, the Sassanids appear to have neglected Mesopotamia.

Mesopotamia is in ruins by the time the enfeebled Sassanid Empire falls to Muslim Arab warriors, and Sumero-Akkadian civilization is entirely extinguished.

Sassanid neglect of the canals and irrigation ditches vital for agriculture has allowed the rivers to flood, and parts of the land have become sterile.

Mesopotamian culture nevertheless passes on many traditions to the West.

The basic principles of mathematics and astronomy, the coronation of kings, and such symbols as the tree of life, the Maltese cross, and the crescent are part of Mesopotamia's legacy.