The continuous troubles in the west cause Seleucid control in the far eastern part of the empire to weaken.

Antiochus makes his eldest son king in the east in 280, but he proves incompetent.

Ptolemy Keraunus had cajoled his half-sister into marrying him, but, on entering Cassandreia, he had promptly executed her two younger sons.

Arsinoe escapes.

Philetaerus has enjoyed a far larger measure of independence than he had hitherto enjoyed under Lysimachus.

The territory Philetaerus controls is as quite small—no more than Pergamon and its environs—and it is largely of necessity that he curries favor with the first Seleucid kings.

His gifts to the temples at Delphi, Greece, and on the island of Delos, in the Aegean Sea, secure for his family some prestige outside of Anatolia.

The slackening of the Seleucid grip on Asia Minor presents Philetaerus with the opportunity to increase the area under his control.

Ephesus had revolted after the treacherous death of Agathocles, giving the Hellenistic king of Syria and Mesopotamia Seleucus I Nicator in 281 BCE an opportunity for removing and killing Lysimachus, his last rival, at the Battle of Corupedium.

The town again is named Ephesus after the death of Lysimachus, and thus becomes part of the Seleucid Empire.

The twelve Achaean cities of the northern Peloponnese had organized a league by the fourth century BCE to protect themselves against piratical raids from across the Corinthian Gulf, but this league had fallen apart after the death of Alexander the Great.

The ten surviving cities—Dyme, Patrae, Tritaea, and Pherae; joined by Aegium, Bura, and Cerynea—renew their alliance in 280 BCE.

This second, more powerful Achaean league, headed now by a single general instead of two, comprises the cities of Achaea and most of the rest of the Peloponnesus except for Corinth, which remains a Macedonian possession, and Sparta, which remains independent.

Annual voting for leadership is by cities, with representation proportionate to population.

Patras (Greek: Patrai), an important commercial center located on the northern shore of the Peloponnesus, about one hundred miles (one hundred and eighty kilometers) west of Athens, is the primary city among the league’s Peloponnesian participants.

Cineas, a Thessalian who serves as chief adviser to Pyrrhus, attempts, without success, to dissuade Pyrrhus from crossing to Italy in 281 BCE with twenty elephants and about twenty-five thousand highly trained soldiers.

In the first meeting of Roman and Greek armies, Pyrrhus wins a complete, if costly, victory in 280 BCE over a Roman army at Heraclea.

After stirring up revolt among the Samnites, he sends Cineas to Rome to negotiate a peace.

The Etruscans of Volsinii, with their allies the Vulcientes, again take up arms against Rome, but this attempt ends in their final subjugation in 280 BCE.

Pliny tells an absurd story, taken from the Greek writer Metrodorus of Scepsis, that the object of the Romans in capturing Volsinii was to make themselves masters of two thousand statues that it contained.

The story, however, suffices to show that the Volsinians had attained great wealth, luxury, and art.

This is confirmed by Valerius Maximus, who also adds that this luxury was the cause of their ruin, by making them so indolent that they at length suffered the management of their commonwealth to be usurped by slaves.

The attempted revolution apparently began with the admission of freedmen into the army, which must have been in 280 BCE.

Ptolemy II Philadelphus, the second Macedonian king of Egypt, attacks the Syrian forces of Antiochos at their capital, Damascus, badly defeating them in 279 and gaining a sizable amount of territory in Palestine.

Ptolemy's aggressions cause continuous friction with Antiochus, who in 279 somehow loses Miletus, in southwestern Asia Minor, to Ptolemy.

Macedon again falls into a state of internal confusion, intensified by a coalition of Gallic (Celtic) and Thracian marauders from the north, under the command of Bolgius, who overrun the country.

Ptolemy Keraunus offers battle and is captured and decapitated.