The Knights win another victory in the next year over a Turkish fleet poised to invade Rhodes.

Pope John XXII rewards Schwarzburg by restoring him to half the post of grand preceptor of Cyprus, whence he had been dismissed two years earlier (the other half going to Maurice of Pagnac) for ten years, and promised the commandery of Kos, if he can capture it.

The victory at Chios is all the more significant, according to the historian Mike Carr, because it had been achieved at the initiative of the Hospitallers and the Zaccarias, without any support or funding by other Western powers, most notably the Papacy, which is still embroiled in plans to launch a Crusade to the Holy Land.

It nevertheless influences the strategic calculations of Western powers, and efforts begin to form a Christian naval league to counter Turkish piracy.

The defeat off Chios cannot halt the rise of Aydinid power in the immediate future, however.

The Zaccarias will soon after be forced to surrender their mainland outpost of Smyrna to Mehmed's son Umur Beg, under whose leadership Aydinid fleets will roam the Aegean for the next two decades, until the Smyrniote crusades (1343–1351) break the Aydinid emirate's power.