The epidemic of encephalitis lethargica that began …

Years: 1928 - 1928

The epidemic of encephalitis lethargica that began in 1919 -- or perhaps as early as 1915 -- had wound down by 1927 and ends definitively in 1928, having claimed an attributed 500,000 deaths and 1,000,000 cases of neurological impairment, which affects males more than females.

First described by the neurologist Constantin von Economo (1876-1931) in 1917, EL attacks the brain, leaving some victims in a statue-like condition, speechless and motionless.

An atypical form of encephalitis, also known as "sleepy sickness" or as "sleeping sickness" (though different from the sleeping sickness transmitted by the tsetse fly), EL is a devastating illness that has swept the world in the 1920s; it now vanishes as quickly as it had appeared.

One theory holds encephalitis lethargica as the explanation for the symptoms of the afflicted in New England during the 1600's, which ultimately resulted in the Salem Witch Trials.

The symptoms --characterized by increasing languor, apathy, and drowsiness, passing into lethargy -- are consistent.

(No recurrence of the epidemic has since been reported, though isolated cases continue to occur.)

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