A latter plague incident from 270 involves the death of Emperor Claudius II Gothicus, though it is unknown if this was the same plague as the so-called Plague of Cyprian or a different outbreak.

The Historia Augusta (unreliable, but the only history we have for this age) states: "in the consulship of Antiochianus and Orfitus the favor of heaven furthered Claudius' success. For a great multitude, the survivors of the barbarian tribes, who had gathered in Haemimontum, were so stricken with famine and pestilence that Claudius now scorned to conquer them further.... during this same period the Scythians attempted to plunder in Crete and Cyprus as well, but everywhere their armies were likewise stricken with pestilence and so were defeated."