Lancaster, after returning to England in November 1360, falls ill early the next year, and on March 23 dies at Leicester Castle.

It is likely that the cause of death is the plague, which this year is making a second visitation of England.

Lancaster was married in 1330 to Isabella, daughter of Henry, Lord Beaumont.

The two had no sons, but two daughters: Maud and Blanche.

While Maud is married to William I, Duke of Bavaria, Blanche had married Edward III's son John of Gaunt.

Gaunt ends up inheriting Lancaster's possessions and ducal title, but it will not be until 1377, when the dying King Edward III is largely incapacitated, that he is able to restore the palatinate rights for the county of Lancaster.

When Gaunt's son Henry of Bolingbroke usurps the crown in 1399 and becomes Henry IV, the vast Lancaster inheritance, including the Lordship of Bowland, will be merged with the crown as the Duchy of Lancaster.