A major cholera outbreak occurs in China in 1669.

Yue Xianyang, who serves as a senior physician of the royal court of the Qing Dynasty in Beijing, establishes Tong Ren Tang, a pharmaceutical company.

Tong Ren Tang is today the largest producer of traditional Chinese medicine.

Residents are allowed to return to their original homes in 1669, when the government lifts the ban on settlement following a request by the Governor-General of Guangdong and Guangxi Zhou Youde and Governor of Guangdong Wang Lairen.

Only sixteen hundred and forty-eight of those who left are said to have returned when the evacuation order is rescinded.

The Fortress of Kolárovo, with the inhabitants of Kolárovo fearing new attacks by Turks, is between 1662-1664 modernized again.

Inside are stone accommodation houses and stone stores for gunpowder and guns.

At this time there are one hundred and thirty mercenaries behind the walls under the command of Matej Frühwirtha.

Turkish units in 1669 burn the eastern part of Kolárovo.

The Jat people under the leader Gokula rebel against their powerful Mughal overlords.

The rebellion is a result of political provocation aggravated by economic discontent, and further aggravated by religious persecution and discrimination.

The whole district is in disorder for a year until the rebellion is suppressed by a strong imperial force under Hasan Ali Khan, the new faujdar of Mathura.

Gokula is put to death by dismemberment.

Yohannes acts harshly towards Europeans due to the violent religious controversy that Catholic missionaries had caused in Ethiopia under the reign of his grandfather Susenyos.

He convokes a church council in 1669 in Gondar, directing Gerazmach Mikael to expel all of the Catholics still living in Ethiopia; those who do not embrace the beliefs of the Ethiopian Church are exiled to Sennar.

His reign sees the execution of six Franciscans sent by Pope Alexander VII to succeed in converting Ethiopia to Catholicism where the Jesuits had failed thirty years before.

Yohannes favors Armenian visitors, whose beliefs also embrace Miaphysitism, and are in harmony with the Ethiopian Church.

These include one Murad, who undertakes a number of diplomatic missions for the Emperor.

The past twenty years of Venetian-Ottoman warfare have seen heavy fighting and much destruction in parts of western Bosnia.

Leopold I Habsburg grants the status and privileges of a university to the Jesuit Academy in Zagreb, the precursor to the modern University of Zagreb.

Antonio Stradivari, believed to have been born in 1644 in the small Italian city of Cremona, had possibly served from 1658 to 1664 as a pupil in workshops of the luthier Nicolò Amati.

At least one Antonio Stradivari label, dated 1666, reads, “Alumnus Nicolais Amati” -- student of Nicolò Amati -- but it has always been controversial as to whether he was an actual apprentice of Nicolò Amati, or merely considered himself a student and admirer of his work in a broader sense.

A crafter of stringed instruments such as violins, cellos, guitars and harps.

Stradivari is generally considered the most significant artisan in this field.

The Latinized form of his surname, Stradivarius, as well as the colloquial, "Strad", is often used to refer to his instruments.

In 1669, Stradivari crafts his first violin.

Twelfth-century Arabian alchemists may have accidentally isolated elemental phosphorus, but the records are unclear.

Henning Brand, a German merchant of Hamburg whose hobby is alchemy, apparently discovers phosphorus in 1669 during his quest for the philosopher's stone.

He had allowed fifty buckets of urine to stand until they putrefied and “bred worms”, and then boiled the urine down to a paste and heated it with sand, thereby distilling elemental phosphorus from the mixture.

Brand reports his discovery in a letter to his compatriot, the philosopher, mathematician, and political advisor Gottfried Wilhelm Leibniz.

Subsequent demonstrations of this element and its ability to glow in the dark, or “phosphoresce”, excite public interest.

The element, which glows because of its rapid oxidation, is named for Greek fosforos, or phosphorous, light bringing.