The long-term effects of the Plague of …

Years: 544 - 555
The long-term effects of the Plague of Justinian on European and Christian history will be enormous.

As the disease spreads to port cities around the Mediterranean, the struggling Goths are reinvigorated and their conflict with Constantinople enters a new phase.

The plague weakens the Empire at a critical point, when Justinian's armies have nearly retaken all of Italy and the western Mediterranean coast; the evolving conquest would have reunited the core of the Western Roman Empire with the Eastern Roman Empire.

Although the conquest occurs in 554, the reunification will not last long.

In 568, the Lombards will invade Northern Italy, defeat the small imperial army that had been left behind, and establish the Kingdom of the Lombards.

The plague may have also contributed to the success of the Arabs a few generations later in the Byzantine-Arab Wars.

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