Ankmachis is the second Pharaoh of the rebel Thirty-fifth dynasty, which controls much of Lower Egypt during the reigns of Ptolemies IV and V. Believed to be the son of Harmachis, who had declared independence around 205 BCE, his rule had begun in approximately 199.

He had held Lykopolis in 197 but was later forced to withdraw to Thebes.

The civil war between the northern and southern areas of Egypt ends with the arrest of Ankmachis by the Ptolemaic general Conanus, but the underlying grievances continue and there will be riots again later in the dynasty.