Abdal-Latif Mirza does not remain loyal to his father.

Angry over the fact that he is to be passed over in the transfer of rule of Samarkand, he revolts while Ulugh Beg is marching to retake Khorasan.

He defeats his father at Dimashq, near Samarkand, in the fall of 1449.

Ulugh Beg later decides to surrender himself, and Abdal-Latif Mirza grants him permission to take a pilgrimage to Mecca, but while Ulugh Beg is on his way he is ordered murdered by his son and is beheaded in October.

(Eventually, his reputation will be rehabilitated by his relative, 'Abdullah (1450–1451), who will place Ulugh Beg's remains in the tomb of Timur in Samarkand, where they will be found by archeologists in 1941.)

This earns Abdal-Latif Mirza the infamous nickname "Padarkush" (from Tajik "patricide").

A few days later he also has his brother 'Abd al-'Aziz killed.

In this manner he becomes ruler of Transoxiana.